About PreTRM®—a Simple Blood Test


Predicting early enables proactive interventions to help better inform decisions made in managing the patient’s pregnancy.  

Sera Prognostics developed a biomarker signature for sPTB using proteomic technology. The PreTRM test is the first, and only clinically validated blood test to predict spontaneous preterm birth (sPTB) risk by measuring proteins that are over- or under-expressed and are predictive of premature birth (or delivery).

Sera’s PreTRM test is highly predictive of preterm delivery in asymptomatic, singleton pregnancies where blood is drawn at 19-20 weeks gestational age, with reported spontaneous preterm birth prediction Area Under the Curve (AUC) ranging between 0.75 and 0.93.5

Test early

Performed between 19 and 20 weeks of pregnancy

Get Individual Risk Results

Reported as percentage indicating risk of delivering prematurely — before 37 weeks

Take Action Early

Results delivered in 7-10 days from Sera Prognostics' CLIA laboratory

Example PreTRM Results

About Our Laboratory

Sera Prognostics' laboratory is a CLIA Laboratory (Clinical Laboratory Improvement Act) performing high-complexity, proteomic testing. The PreTRM test is performed using liquid chromatography-tandem mass spectrometry (LC-MS/MS) to simultaneously measure multiple proteins in patients' blood. These proteins have been proven to be associated with spontaneous preterm birth.5 The concentrations of individual proteins are then combined to establish a PreTRM test result that represents an individual woman’s risk of spontaneous preterm delivery for her current pregnancy.