While you’re considering the PreTRM® test, we thought you might like to see what the test results will look like. The sample test results below may help you better understand what your own test results will look like. You can ask your doctor for a copy of the results after you’ve reviewed your individual risk score together.

Test overview

There are two proteins in your body, IBP4 and SHBG, that act very differently in women who go on to have term babies versus those who go on to have premature babies. During week 19 and 20 of your pregnancy, there are much higher levels of IBP4 and much lower levels of SHBG in women who have premature babies. We combine those measures in a proprietary, mathematical algorithm or predictor. The results are then compared to the baseline or average risk of most pregnant women expressed in a percentage of preterm risk and a comparative risk against the average population.

With the PreTRM test you could know — weeks before your due date — your personal percentage of risk for premature birth.

As you can see, the average risk or baseline for most women is 7.3% so your rate of risk could be the same or move further away from that baseline.

On the sample test result shown here, the test subject scored above the baseline with a 22% risk of delivery before 37 weeks of pregnancy.  This means she is 3 times more likely to deliver premature than the normal population.

Your test results and your pregnancy

Patients who have received results falling within the normal baseline (around 7%) reported feeling reassured that they can put this concern on the backburner.

If you are at higher risk, the good news is that knowing gives you and your doctor time to take steps to manage your risk with the goal of giving your baby the best start in life.

Premature birth care programs that have been studied in selected groups of pregnant women have shown some benefit to help prolong pregnancy, such as:

  • Increased office visits
  • Cervical length screening and monitoring. A shortened cervix may indicate delivery is starting.
  • Cervical cerclage:  a “stitch” put into the cervix to help keep it closed
  • Cervical pessary: ring-shaped device placed around the cervix to provide support
  • Progesteronehormone (according to professional guidelines)
  • “Pregnancy Centering” support groups of moms and caregivers for physical, emotional and medical issues
  • Stress reduction
  • Stop smoking

Signs of Premature Labor

While all patients should know the signs and symptoms of preterm labor, it is especially important for women at higher risk to be attentive to premature labor symptoms. Call your doctor right away if you think you are having any of the following symptoms of labor. And be sure and talk to your doctor about other symptoms to look for that may indicate you’re going into labor.

Contractions: the abdomen tightens like a fist every 10 minutes or more often

Change in vaginal discharge: leaking fluid or bleeding

Pelvic pressure: the feeling that the baby is pushing down

Backache: usually in your lower back

Cramps: that feel like a menstrual period

Abdominal cramps: with or without diarrhea

The following are two actual patient case studies showing the care and outcome based on the results of their PreTRM test and knowing their risk of premature delivery.

​Case Study: 7.3% risk

Veronica — 36-year-old woman

  • Conceived by IVF
  • Prior miscarriages at 8 & 10 weeks
  • Prior Laparoscopy / hysteroscopy

 Test Result: PreTRM test showed a near normal 7.3% risk (7% is normal) of preterm delivery prior to 37 weeks 

 Veronica and her doctor agreed on a plan to continue through her pregnancy.

Each woman and each pregnancy is different. After reviewing her PreTRM test result, she and her doctor made a plan based on her individual history and current health.

Veronica’s plan included:

  • Single Ultrasound Cervical Length Measurement
  • Routine clinical follow-up
  • Awareness and observation of prematurity symptom.

Veronica delivered a full term, healthy baby at 40 weeks and 3 days.

Case Study:  46% risk

Sally G.  — 28-year-old woman, 2nd pregnancy

  • No significant medical history
  • Previous pregnancy — Full term vaginal delivery at 39 weeks
  • History of cone biopsy
  • Slightly overweight — BMI 26.5

PreTRM® test results showed a 46% risk or (6.3 times above the average population) of preterm delivery prior to 37 weeks. Sally and her doctor agreed on a plan to help prolong her pregnancy Each woman and each pregnancy is different. If you know you’re at increased risk, you and your doctor can create a plan to manage your risk. This could include more frequent visits with your ObGyn, and seeing a high- risk pregnancy specialist (Maternal Fetal Medicine). Sally’s plan included:

  • Ultrasound Cervical Length monitoring
  • Possible Progesterone as indicated by Cervical Length
  • Awareness and observation of prematurity symptoms. It is especially important for women at higher risk to pay special attention to premature labor symptoms.

Sally delivered a full term, healthy baby at 40 wees.

The PreTRM test does not prolong pregnancy

The PreTRM test is a diagnostic tool – not a medical therapy.  Having the test makes you and your doctor aware of your risk and take appropriate measures to manage risk with the goal of giving your baby the best start in life.

However, without the test, you could be one of the 80% of women who never thought premature birth could happen to them until they went into early labor unexpectedly. Something to consider seriously before you reach your 19th week of pregnancy.

Birth is a complex and wonderful process. It goes without saying that everyone hopes for a healthy, full term baby so it's important to know if you’re at risk for an early delivery. Remember, knowing that your baby may deliver prematurely gives you the power to prepare, get extra care for your pregnancy, and give your baby the best start in life.